Tumor suppression involves down-regulation of interleukin 3 expression in hybrids between autocrine mastocytoma and interleukin 3-dependent parental mast cells.

Interleukin 3 (IL-3)-dependent PB-3c mouse mastocytes can be transformed by the v-Ha-ras oncogene to generate autocrine IL-3-producing mastocytomas. Hybrid cell lines were constructed by fusing an IL-3-producing mastocytoma cell line with its IL-3-dependent normal parental cell. Unlike the mastocyto...

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Detalhes bibliográficos
Main Authors: Diamantis, I D, Nair, A P, Hirsch, H H, Moroni, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298482/
https://ncbi.nlm.nih.gov/pubmed/2512578
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