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The insulin receptor as a transmitter of a mitogenic signal in Chinese hamster ovary CHO-K1 cells.

Insulin is the only hormone required for continued growth of Chinese hamster ovary CHO-K1 cells in the defined medium M-F12. When CHO-K1 cells are incubated in M-F12 without insulin for 48-72 hr, the cells accumulate in G1. In response to physiological concentrations of insulin an 18-fold increase i...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Mamounas, M, Gervin, D, Englesberg, E
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1989
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298481/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2687878/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9294
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