Ethylene Glycol Monomethyl Ether–Induced Toxicity Is Mediated through the Inhibition of Flavoprotein Dehydrogenase Enzyme Family

Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In order to gain mechanistic understanding of EGME-indu...

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Autores principales: Takei, Makoto, Ando, Yosuke, Saitoh, Wataru, Tanimoto, Tomoe, Kiyosawa, Naoki, Manabe, Sunao, Sanbuissho, Atsushi, Okazaki, Osamu, Iwabuchi, Haruo, Yamoto, Takashi, Adam, Klaus-Peter, Weiel, James E., Ryals, John A., Milburn, Michael V., Guo, Lining
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Reproductive and Developmental Toxicology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984528/
https://ncbi.nlm.nih.gov/pubmed/20616209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq211
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