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Ethylene Glycol Monomethyl Ether–Induced Toxicity Is Mediated through the Inhibition of Flavoprotein Dehydrogenase Enzyme Family

Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In order to gain mechanistic understanding of EGME-indu...

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Detalhes bibliográficos
Main Authors: Takei, Makoto, Ando, Yosuke, Saitoh, Wataru, Tanimoto, Tomoe, Kiyosawa, Naoki, Manabe, Sunao, Sanbuissho, Atsushi, Okazaki, Osamu, Iwabuchi, Haruo, Yamoto, Takashi, Adam, Klaus-Peter, Weiel, James E., Ryals, John A., Milburn, Michael V., Guo, Lining
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984528/
https://ncbi.nlm.nih.gov/pubmed/20616209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq211
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