PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice

BACKGROUND: Inflammation of adipose tissue (AT) has been recently accepted as a first step towards obesity-mediated insulin resistance. We could previously show that mice fed with high fat diet (HFD) develop systemic insulin resistance (IR) and glucose intolerance (GI) associated with CD4-positive T...

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Main Authors: Foryst-Ludwig, Anna, Hartge, Martin, Clemenz, Markus, Sprang, Christiane, Heß, Katharina, Marx, Nikolaus, Unger, Thomas, Kintscher, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Original Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984486/
https://ncbi.nlm.nih.gov/pubmed/20955583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-9-64
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