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Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

Nitric oxide, which mediates influences of numerous neurotransmitters and modulators on vascular smooth muscle and leukocytes, can be formed in the brain from arginine by an enzymatic activity that stoichiometrically generates citrulline. We show that glutamate and related amino acids, such as N-met...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Bredt, D S, Snyder, S H
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298426/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2573074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.9030
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