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An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation
In humans, septal defects are among the most prevalent congenital heart diseases, but their cellular and molecular origins are not fully understood. We report that transcription factor Tbx5 is present in a subpopulation of endocardial cells and that its deletion therein results in fully penetrant, d...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2984205/ https://ncbi.nlm.nih.gov/pubmed/20974940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914888107 |
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