High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity

As influenza viruses have developed resistance towards current drugs, new inhibitors that prevent viral replication through different inhibitory mechanisms are useful. In this study, we developed a screening procedure to search for new antiinfluenza inhibitors from 1,200,000 compounds and identified...

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Autors principals: Su, Ching-Yao, Cheng, Ting-Jen R., Lin, Meng-I., Wang, Shi-Yun, Huang, Wen-I., Lin-Chu, Shao-Ying, Chen, Yu-Hou, Wu, Chung-Yi, Lai, Michael M. C., Cheng, Wei-Chieh, Wu, Ying-Ta, Tsai, Ming-Daw, Cheng, Yih-Shyun E., Wong, Chi-Huey
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Physical Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984200/
https://ncbi.nlm.nih.gov/pubmed/20974907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013592107
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