Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system

Drug addiction is a chronic relapsing disorder characterized by compulsive drug seeking and use. Environmental conditioning factors are among the major determinants of relapse in abstinent cocaine users. Here we describe a role of the neuropeptide S (NPS) system in regulating relapse. In rats with a...

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Detalhes bibliográficos
Main Authors: Kallupi, Marsida, Cannella, Nazzareno, Economidou, Daina, Ubaldi, Massimo, Ruggeri, Barbara, Weiss, Friedbert, Massi, Maurizio, Marugan, Juan, Heilig, Markus, Bonnavion, Patricia, de Lecea, Luis, Ciccocioppo, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984152/
https://ncbi.nlm.nih.gov/pubmed/20974945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004100107
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