Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β

Nanoparticles are increasingly used in various fields, including biomedicine and electronics. One application utilizes the opacifying effect of nano-TiO(2), which is frequently used as pigment in cosmetics. Although TiO(2) is believed to be biologically inert, an emerging literature reports increase...

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Main Authors: Yazdi, Amir S., Guarda, Greta, Riteau, Nicolas, Drexler, Stefan K., Tardivel, Aubry, Couillin, Isabelle, Tschopp, Jürg
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984140/
https://ncbi.nlm.nih.gov/pubmed/20974980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008155107
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