Experimental pancreatitis is mediated by low-affinity cholecystokinin receptors that inhibit digestive enzyme secretion.
Rats infused with a supramaximally stimulating dose of the cholecystokinin (CCK) analog caerulein develop acute edematous pancreatitis. Using CCK-JMV-180, a recently developed CCK analog that acts as an agonist at high-affinity CCK receptors but antagonizes the effect of CCK at low-affinity receptor...
में बचाया:
| में प्रकाशित: | Proc Natl Acad Sci U S A |
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| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
1989
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2479032/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8968 |
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