Production of human glucocerebrosidase in mice after retroviral gene transfer into multipotential hematopoietic progenitor cells.
The human glucocerebrosidase (GC) gene has been transferred efficiently into spleen colony-forming unit (CFU-S) multipotential hematopoietic progenitor cells, and production of human GC RNA and protein has been achieved in transduced CFU-S colonies. High-titer retroviral vectors containing the human...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1989
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2573069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8912 |
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