Production of human glucocerebrosidase in mice after retroviral gene transfer into multipotential hematopoietic progenitor cells.

The human glucocerebrosidase (GC) gene has been transferred efficiently into spleen colony-forming unit (CFU-S) multipotential hematopoietic progenitor cells, and production of human GC RNA and protein has been achieved in transduced CFU-S colonies. High-titer retroviral vectors containing the human...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Correll, P H, Fink, J K, Brady, R O, Perry, L K, Karlsson, S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2573069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8912
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