Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells.

Long-term stable expression of foreign genetic sequences transferred into hematopoietic stem cells by using retroviral vectors constitutes a relevant model for somatic gene therapy. Such stability of expression may depend on vector design, including the presence or absence of specific sequences with...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lim, B, Apperley, J F, Orkin, S H, Williams, D A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298396/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2573068/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8892
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