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Small RING Finger Proteins RBX1 and RBX2 of SCF E3 Ubiquitin Ligases: The Role in Cancer and as Cancer Targets
The SCF (Skp1–cullin–F-box proteins), also known as CRL (cullin-based RING ligase), is the largest family of E3 ubiquitin ligases that mediate approximately 20% ubiquitinated protein substrates for 26S proteasome degradation. Through promoting timely degradation of many key regulatory proteins, SCF...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2983490/ https://ncbi.nlm.nih.gov/pubmed/21103004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910382776 |
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