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The Pore Structure of the Closed RyR1 Channel

Using single particle electron cryomicroscopy, several helices in the membrane-spanning region of RyR1, including an inner transmembrane helix, a short pore helix, and a helix parallel to the membrane on the cytoplasmic side, have been clearly resolved. Our model places a highly conserved glycine (G...

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Détails bibliographiques
Auteurs principaux: Ludtke, Steven J., Serysheva, Irina I., Hamilton, Susan L., Chiu, Wah
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2983469/
https://ncbi.nlm.nih.gov/pubmed/16084392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2005.06.005
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