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The cell biology of polycystic kidney disease

Polycystic kidney disease is a common genetic disorder in which fluid-filled cysts displace normal renal tubules. Here we focus on autosomal dominant polycystic kidney disease, which is attributable to mutations in the PKD1 and PKD2 genes and which is characterized by perturbations of renal epitheli...

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Detalhes bibliográficos
Main Authors: Chapin, Hannah C., Caplan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2983067/
https://ncbi.nlm.nih.gov/pubmed/21079243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006173
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