Prognostic significance of nucleophosmin mutations and FLT3 internal tandem duplication in adult patients with cytogenetically normal acute myeloid leukemia

BACKGROUND: Nucleophosmin (NPM1) gene and fms-like tyrosine kinase 3 gene-internal tandem duplication (FLT3-ITD) mutations are the most frequent mutations in patients with cytogenetically normal (CN)-AML. We analyzed the prognostic impact of these mutations and their interactions in adults with CN-A...

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Detalhes bibliográficos
Main Authors: Kim, Yeo-Kyeoung, Kim, Hee-Nam, Lee, Se Ryeon, Ahn, Jae-Sook, Yang, Deok-Hwan, Lee, Je-Jung, Lee, Il-Kwon, Shin, Myung-Geun, Kim, Hyeoung-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2983002/
https://ncbi.nlm.nih.gov/pubmed/21120161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/kjh.2010.45.1.36
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