BMP signaling modulates hedgehog-induced secondary heart field proliferation

Sonic hedgehog signaling in the secondary heart field has a clear role in cardiac arterial pole development. In the absence of hedgehog signaling, proliferation is reduced in secondary heart field progenitors, and embryos predominantly develop pulmonary atresia. While it is expected that proliferati...

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Bibliographic Details
Main Authors: Dyer, Laura A., Makadia, Frini A., Scott, Alexandria, Pegram, Kelly, Hutson, Mary R., Kirby, Margaret L.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982885/
https://ncbi.nlm.nih.gov/pubmed/20920499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.09.021
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