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Regulation of lin-4 miRNA Expression, Organismal Growth and Development by a Conserved RNA Binding Protein in C. elegans

Transcription and multiple processing steps are required to produce specific 22 nucleotide microRNAs (miRNAs) that can regulate the expression of target genes. In C. elegans, mature lin-4 miRNA accumulates at the end of the first larval stage to repress its direct targets lin-14 and lin-28, allowing...

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Detalhes bibliográficos
Main Authors: Bracht, John R., Van Wynsberghe, Priscilla M., Mondol, Vanessa, Pasquinelli, Amy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982876/
https://ncbi.nlm.nih.gov/pubmed/20937268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.10.003
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