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Lipoic Acid Synthesis: A New Family of Octanoyltransferases Generally Annotated as Lipoate Protein Ligases

Bacillus subtilis lacks a recognizable homologue of the LipB octanoyltransferase, an enzyme essential for lipoic acid synthesis in Escherichia coli. LipB transfers the octanoyl moiety from octanoyl-acyl carrier protein to the lipoyl domains of the 2-oxoacid dehydrogenases via a thioester-linked octa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Christensen, Quin H., Cronan, John E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982868/
https://ncbi.nlm.nih.gov/pubmed/20882995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101215f
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