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Intraspecies Prion Transmission Results in Selection of Sheep Scrapie Strains

BACKGROUND: Sheep scrapie is caused by multiple prion strains, which have been classified on the basis of their biological characteristics in inbred mice. The heterogeneity of natural scrapie prions in individual sheep and in sheep flocks has not been clearly defined. METHODOLOGY/PRINCIPAL FINDINGS:...

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Detalhes bibliográficos
Main Authors: Yokoyama, Takashi, Masujin, Kentaro, Schmerr, Mary Jo, Shu, Yujing, Okada, Hiroyuki, Iwamaru, Yoshifumi, Imamura, Morikazu, Matsuura, Yuichi, Murayama, Yuichi, Mohri, Shirou
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982847/
https://ncbi.nlm.nih.gov/pubmed/21103326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015450
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