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Intraspecies Prion Transmission Results in Selection of Sheep Scrapie Strains

BACKGROUND: Sheep scrapie is caused by multiple prion strains, which have been classified on the basis of their biological characteristics in inbred mice. The heterogeneity of natural scrapie prions in individual sheep and in sheep flocks has not been clearly defined. METHODOLOGY/PRINCIPAL FINDINGS:...

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Bibliografische gegevens
Hoofdauteurs: Yokoyama, Takashi, Masujin, Kentaro, Schmerr, Mary Jo, Shu, Yujing, Okada, Hiroyuki, Iwamaru, Yoshifumi, Imamura, Morikazu, Matsuura, Yuichi, Murayama, Yuichi, Mohri, Shirou
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982847/
https://ncbi.nlm.nih.gov/pubmed/21103326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015450
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