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Copper and the ACE1 regulatory protein reversibly induce yeast metallothionein gene transcription in a mouse extract.

We describe a cell-free system in which the transcription of the yeast metallothionein gene is inducible by the addition of metal ions plus a specific regulatory protein. Efficient transcription requires the complete yeast ACE1 metalloregulatory protein, including both its DNA-binding and transactiv...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Culotta, V C, Hsu, T, Hu, S, Fürst, P, Hamer, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298284/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2682650/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8377
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