A Post-Burst Afterdepolarization Is Mediated by Group I Metabotropic Glutamate Receptor-Dependent Upregulation of Ca(v)2.3 R-Type Calcium Channels in CA1 Pyramidal Neurons

Activation of group I metabotropic glutamate receptors (subtypes mGluR1 and mGluR5) regulates neural activity in a variety of ways. In CA1 pyramidal neurons, activation of group I mGluRs eliminates the post-burst afterhyperpolarization (AHP) and produces an afterdepolarization (ADP) in its place. He...

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Detalhes bibliográficos
Main Authors: Park, Jin-Yong, Remy, Stefan, Varela, Juan, Cooper, Donald C., Chung, Sungkwon, Kang, Ho-Won, Lee, Jung-Ha, Spruston, Nelson
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982802/
https://ncbi.nlm.nih.gov/pubmed/21103408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000534
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