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Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion

H3K9 methylation has been linked to a variety of biological processes including position-effect variegation, heterochromatin formation and transcriptional regulation. To further understand the function of H3K9 methylation, we have identified and characterized MPP8 as a methyl-H3K9-binding protein. M...

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Detalhes bibliográficos
Main Authors: Kokura, Kenji, Sun, Lidong, Bedford, Mark T, Fang, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982762/
https://ncbi.nlm.nih.gov/pubmed/20871592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.239
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