Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways.

Distinct genes encode alpha and beta platelet-derived growth factor (PDGF) receptors that differ in their abilities to be triggered by three dimeric forms of the PDGF molecule. We show that PDGF-receptor mitogenic function can be reconstituted in a naive hematopoietic cell line by introduction of ex...

Descripción completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Matsui, T, Pierce, J H, Fleming, T P, Greenberger, J S, LaRochelle, W J, Ruggiero, M, Aaronson, S A
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554309/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8314
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!