Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease.
Protease nexin-1 (PN-1) is a cell-secreted protein that inhibits certain proteases, particularly thrombin, by forming SDS-stable complexes with the catalytic site serine of the protease. PN-1 was recently shown to be identical to a glial-derived neurite-promoting factor/glial-derived nexin present i...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1989
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298265/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2813392/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8284 |
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