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Mutation of the proteolipid protein gene PLP in a human X chromosome-linked myelin disorder.

Myelin is a highly specialized membrane unique to the nervous system that ensheaths axons to permit the rapid saltatory conduction of impulses. The elaboration of a compact myelin sheath is disrupted in a diverse spectrum of human disorders, many of which are of unknown etiology. The X chromosome-li...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hudson, L D, Puckett, C, Berndt, J, Chan, J, Gencic, S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298228/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2479017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.20.8128
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