Correlation Between Anti-Myelin Proteolipid Protein (PLP) Antibodies and Disease Severity in Multiple Sclerosis Patients With PLP Response-Permissive HLA Types

The most prominent pathological features of multiple sclerosis (MS) are demyelination and neurodegeneration. The exact pathogenesis of MS is unknown, but it is generally regarded as a T cell-mediated autoimmune disease. Increasing evidence, however, suggests that other components of the immune syste...

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Hauptverfasser:	Judith M. Greer, Elisabeth Trifilieff, Michael P. Pender
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2020-08-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	antibody myelin proteolipid protein multiple sclerosis disease severity HLA type
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fimmu.2020.01891/full
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