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Structural bases for the interaction of frataxin with the central components of iron–sulphur cluster assembly

Reduced levels of frataxin, an essential protein of as yet unknown function, are responsible for causing the neurodegenerative pathology Friedreich's ataxia. Independent reports have linked frataxin to iron–sulphur cluster assembly through interactions with the two central components of this ma...

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Detalhes bibliográficos
Main Authors: Prischi, Filippo, Konarev, Petr V., Iannuzzi, Clara, Pastore, Chiara, Adinolfi, Salvatore, Martin, Stephen R., Svergun, Dmitri I., Pastore, Annalisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982165/
https://ncbi.nlm.nih.gov/pubmed/20981023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1097
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