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Structural bases for the interaction of frataxin with the central components of iron–sulphur cluster assembly

Reduced levels of frataxin, an essential protein of as yet unknown function, are responsible for causing the neurodegenerative pathology Friedreich's ataxia. Independent reports have linked frataxin to iron–sulphur cluster assembly through interactions with the two central components of this ma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Prischi, Filippo, Konarev, Petr V., Iannuzzi, Clara, Pastore, Chiara, Adinolfi, Salvatore, Martin, Stephen R., Svergun, Dmitri I., Pastore, Annalisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982165/
https://ncbi.nlm.nih.gov/pubmed/20981023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1097
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