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The role of PAK-1 in activation of MAP kinase cascade and oncogenic transformation by Akt

The activity of protein kinase B, also known as Akt, is commonly elevated in human malignancies and plays a crucial role in oncogenic transformation. The relationship between Akt and the mitogen-activated protein kinase cascade, which is also frequently associated with oncogenesis, remains controver...

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Hlavní autoři: Somanath, PR, Vijai, J, Kichina, JV, Byzova, T, Kandel, ES
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982142/
https://ncbi.nlm.nih.gov/pubmed/19421139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.114
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