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Interleukin 6 induces secretion of IgG1 by coordinated transcriptional activation and differential mRNA accumulation.

The molecular mechanism by which interleukin 6 (IL-6) induces terminal differentiation of B cells was investigated in a subpopulation of the clonal human B-lymphoblastoid cell line CESS selected for high density of cell surface IgG1. Induction of CESS cells with IL-6 resulted in a 15-fold preferenti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Raynal, M C, Liu, Z Y, Hirano, T, Mayer, L, Kishimoto, T, Chen-Kiang, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1989
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC298206/
https://ncbi.nlm.nih.gov/pubmed/2813375
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