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Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3

During antigen-induced immune responses, human B cells switch isotype from immunoglobulin M (IgM)-IgD to IgG1-4, IgA1-2, or IgE. In the human, no cytokines have yet been demonstrated to act as switch factors for IgG1, IgG2, and IgG3. In this paper, we report that in response to interleukin 10 (IL-10...

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Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191366/
https://ncbi.nlm.nih.gov/pubmed/8294883
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