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Bovine IgG1, but not IgG2, binds to human B cells and inhibits antibody secretion.

We previously observed that milk-derived bovine IgG, but not serum-derived bovine IgG, strongly inhibits antibody secretion by pokeweed mitogen (PWM)-stimulated human peripheral blood mononuclear cells (PBMC). Bovine milk contains a greater percentage of IgG1 (90%) than does bovine serum (53%). To d...

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Detalhes bibliográficos
Main Authors: Nash, G S, MacDermott, R P, Schloemann, S, Bertovich, M J, O'Neal, J, Porter, L, Kulczycki, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385952/
https://ncbi.nlm.nih.gov/pubmed/2312161
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