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The Metabolism and Toxicity of Menthofuran in Rat Liver Slices and in Rats
Menthofuran is a monoterpene present in mint plants that is oxidized by mammalian cytochrome P450 (CYP) to hepatotoxic metabolites. Evidence has been presented that p-cresol and other unusual oxidative products are metabolites of menthofuran in rats, and that p-cresol may be responsible in part for...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981629/ https://ncbi.nlm.nih.gov/pubmed/20945912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100268g |
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