Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis

The selection and soaring spread of Mycobacterium tuberculosis multidrug-resistant (MDR-TB) and extensively drug-resistant strains (XDR-TB) is a severe public health problem. Currently, there is an urgent need for new drugs for tuberculosis treatment, with novel mechanisms of action and, moreover, t...

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Detalhes bibliográficos
Main Authors: Lucarelli, Anna P., Buroni, Silvia, Pasca, Maria R., Rizzi, Menico, Cavagnino, Andrea, Valentini, Giovanna, Riccardi, Giovanna, Chiarelli, Laurent R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981568/
https://ncbi.nlm.nih.gov/pubmed/21085589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015494
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