CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220(NPAT) and HiNF-P

Cell cycle progression into S phase requires the induction of histone gene expression to package newly synthesized DNA as chromatin. Cyclin E stimulation of CDK2 at the Restriction point late in G1 controls both histone gene expression by the p220(NPAT)/HiNF-P pathway and initiation of DNA replicati...

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Main Authors: Mitra, Partha, Ghule, Prachi N., van der Deen, Margaretha, Medina, Ricardo, Xie, Rong-lin, Holmes, William F., Ye, Xin, Nakayama, Keiichi I., Harper, J. Wade, Stein, Janet L., Stein, Gary S., van Wijnen, Andre J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981436/
https://ncbi.nlm.nih.gov/pubmed/19170105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21687
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