Elevated Levels of the Plasmodium yoelii Homologue of Macrophage Migration Inhibitory Factor Attenuate Blood-Stage Malaria

The excessive production of proinflammatory cytokines plays a significant role in the pathogenesis of severe malaria. Mammalian macrophage migration inhibitory factor (MIF) (mMIF) is an immune mediator that promotes a sustained proinflammatory response by inhibiting the glucocorticoid-mediated downr...

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Bibliographic Details
Main Authors: Thorat, Swati, Daly, Thomas M., Bergman, Lawrence W., Burns, James M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981320/
https://ncbi.nlm.nih.gov/pubmed/20837716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00277-10
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