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Biophysical mimicry of lung surfactant protein B by random nylon-3 copolymers

Non-natural oligomers have recently shown promise as functional analogues of lung surfactant proteins B and C (SP-B and SP-C), two helical and amphiphilic proteins that are critical for normal respiration. The generation of non-natural mimics of SP-B and SP-C has previously been restricted to step-b...

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Detalhes bibliográficos
Main Authors: Dohm, Michelle T., Mowery, Brendan P., Czyzewski, Ann M., Stahl, Shannon S., Gellman, Samuel H., Barron, Annelise E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981085/
https://ncbi.nlm.nih.gov/pubmed/20481635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909734n
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