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An MHC class II restriction bias to I-A in CD4 T cell responses is altered to I-E in DM-deficient mice
The MHC-encoded cofactor DM, catalyzes endosomal loading of peptides onto MHC class II molecules. Despite evidence from in vitro experiments that DM acts to selectively edit the repertoire of class II:peptide complexes, the consequence of DM expression in vivo, or a predictive pattern of DM activity...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981066/ https://ncbi.nlm.nih.gov/pubmed/18209058 |
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