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Fruit flies with additional expression of the elongation factor EF-1 alpha live longer.

In Drosophila melanogaster, the decrease in protein synthesis that accompanies aging is preceded by a decrease in elongation factor EF-1 alpha protein and mRNA. Here we show that Drosophila transformed with a P-element vector containing an EF-1 alpha gene under control of hsp70 regulatory sequences...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Shepherd, J C, Walldorf, U, Hug, P, Gehring, W J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298096/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2508089/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7520
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