Fruit flies with additional expression of the elongation factor EF-1 alpha live longer.

In Drosophila melanogaster, the decrease in protein synthesis that accompanies aging is preceded by a decrease in elongation factor EF-1 alpha protein and mRNA. Here we show that Drosophila transformed with a P-element vector containing an EF-1 alpha gene under control of hsp70 regulatory sequences...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Shepherd, J C, Walldorf, U, Hug, P, Gehring, W J
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1989
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298096/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2508089/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7520
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