Promotion of murine hepatocarcinogenesis by testosterone is androgen receptor-dependent but not cell autonomous.
Tfm (testicular feminization) mutant mice lack functional androgen receptors. By studying liver tumor development in Tfm mice, we have shown that the greater susceptibility of male mice relative to female mice for liver tumor induction by N,N-diethylnitrosamine is androgen receptor-dependent. C57BL/...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2798421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7505 |
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