Promotion of murine hepatocarcinogenesis by testosterone is androgen receptor-dependent but not cell autonomous.

Tfm (testicular feminization) mutant mice lack functional androgen receptors. By studying liver tumor development in Tfm mice, we have shown that the greater susceptibility of male mice relative to female mice for liver tumor induction by N,N-diethylnitrosamine is androgen receptor-dependent. C57BL/...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Kemp, C J, Leary, C N, Drinkwater, N R
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1989
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2798421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7505
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