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Structure of the Blm10-20S Proteasome Complex by Cryo-electron Microscopy. Insights into the Mechanism of Activation of Mature Yeast Proteasomes

The 20S proteasome is regulated at multiple levels including association with endogenous activators. Two activators have been described for the yeast 20S proteasome: the 19S regulatory particle and the Blm10 protein. The sequence of Blm10 is 20% identical to the mammalian PA200 protein. Recent studi...

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Detalhes bibliográficos
Main Authors: Iwanczyk, Jack, Sadre-Bazzaz, Kianoush, Ferrell, Katherine, Kondrashkina, Elena, Formosa, Timothy, Hill, Christopher P., Ortega, Joaquin
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980845/
https://ncbi.nlm.nih.gov/pubmed/16952374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.08.010
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