Determination of PF-04928473 in human plasma using liquid chromatography with tandem mass spectrometry

A simple, rapid and sensitive liquid chromatography/tandem mass spectrometric (LC/MS/MS) analytical method was developed for quantification of Hsp90 inhibitor PF-04928473 in human plasma, following administration of its prodrug, PF-04929113. Sample processing involved protein precipitation by additi...

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Bibliographic Details
Main Authors: Jain, Lokesh, Gardner, Erin R., Venitz, Jürgen, Giaccone, Giuseppe, Houk, Brett E., Figg, William D.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980813/
https://ncbi.nlm.nih.gov/pubmed/20951100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.09.017
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