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Rapid Flow Cytometry–Based Structural Maintenance of Chromosomes 1 (SMC1) Phosphorylation Assay for Identification of Ataxia-Telangiectasia Homozygotes and Heterozygotes

BACKGROUND: No rapid reliable method exists for identifying ataxia-telangiectasia (A-T) homozygotes or heterozygotes. Heterozygotes are at an increased risk of cancer and are more sensitive to the effects of ionizing radiation (IR) than the general population. We report a rapid flow cytometry (FC)-b...

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Autors principals: Nahas, Shareef A., Butch, Anthony W., Du, Liutao, Gatti, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980758/
https://ncbi.nlm.nih.gov/pubmed/19147735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2008.107128
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