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Rapid Flow Cytometry–Based Structural Maintenance of Chromosomes 1 (SMC1) Phosphorylation Assay for Identification of Ataxia-Telangiectasia Homozygotes and Heterozygotes

BACKGROUND: No rapid reliable method exists for identifying ataxia-telangiectasia (A-T) homozygotes or heterozygotes. Heterozygotes are at an increased risk of cancer and are more sensitive to the effects of ionizing radiation (IR) than the general population. We report a rapid flow cytometry (FC)-b...

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書誌詳細
主要な著者: Nahas, Shareef A., Butch, Anthony W., Du, Liutao, Gatti, Richard A.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980758/
https://ncbi.nlm.nih.gov/pubmed/19147735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2008.107128
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