ATM protein and p53-serine 15 phosphorylation in ataxia-telangiectasia (AT) patients and at heterozygotes

ATM (ataxia-telangiectasia mutated) gene plays a central role in the DNA-damage response pathway. We characterized the ATM protein expression in immortalized cells from AT and AT-variant patients, and heterozygotes and correlated it with two ATM-dependent radiation responses, G1 checkpoint arrest an...

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Detalles Bibliográficos
Autores principales: Delia, D, Mizutani, S, Panigone, S, Tagliabue, E, Fontanella, E, Asada, M, Yamada, T, Taya, Y, Prudente, S, Saviozzi, S, Frati, L, Pierotti, M A, Chessa, L
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363260/
https://ncbi.nlm.nih.gov/pubmed/10864201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1168
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