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Perfringolysin O Association with Ordered Lipid Domains: Implications for Transmembrane Protein Raft Affinity

Upon interaction with cholesterol, perfringolysin O (PFO) inserts into membranes and forms a rigid transmembrane (TM) β-barrel. PFO is believed to interact with liquid ordered lipid domains (lipid rafts). Because the origin of TM protein affinity for rafts is poorly understood, we investigated PFO r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nelson, Lindsay D., Chiantia, Salvatore, London, Erwin
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980714/
https://ncbi.nlm.nih.gov/pubmed/21081073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.028
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