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Perfringolysin O Association with Ordered Lipid Domains: Implications for Transmembrane Protein Raft Affinity
Upon interaction with cholesterol, perfringolysin O (PFO) inserts into membranes and forms a rigid transmembrane (TM) β-barrel. PFO is believed to interact with liquid ordered lipid domains (lipid rafts). Because the origin of TM protein affinity for rafts is poorly understood, we investigated PFO r...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980714/ https://ncbi.nlm.nih.gov/pubmed/21081073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.028 |
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